Revolutionary Antibacterial Technology

KOITE® technology is an effective solution against bacteria for long term use.

It is safe, effective and there is no antibiotic resistance formation.

KOITE® technology is widely adoptable in health care! First target area for KOITE® treatment is in oral care.

Key facts about oral health provided by WHO
Oral health is a cornerstone of good health.
Most of the oral diseases are caused by bacteria.
Caries
Over 60-90% of school-age children and nearly 100% of adults have or have had dental decay.
Gingivitis
74% of adults suffer from gingivitis, and 21% have deep gum pockets.
Periodontitis
Around the world, the occurrence of severe periodontitis (gum disease) is 11.2 %, which has remained at the same level since 1990.
Peri-implant mucositis
Peri-implant mucositis occurs in 43% of patients after surgery. And, more severe peri-implantitis occurs in 22% of patients post-surgery.
An image from a scanning electron microscope show bristles from a used toothbrush covered in dental plaque
© SPL / Barcroft Media

Biofilm bacterial control is extremely challenging

The challenge is that in a biofilm, what is called an "exopolysaccharide matrix scaffold" protects microbes from external damage. Almost all antibacterial treatments are ineffective.
Resistance formation
Use of antibiotics is impractical due to resistance formation. Even mouth rinses show a cross-resistance formation against the Cholistin antibiotic.
Continuous use
Continuous use of the gold standard antiseptic Chlorhexidine causes dental discoloring, taste change and a reduced immune response.
Preserve normal flora
Maintaining normal bacterial flora is important for health. Disruption in the flora increases the risk of illness. Eliminate bacteria only at tooth level and let normal flora flourish.

Introducing Lumoral®: A proprietary antibacterial prophylaxis

  • Kills harmful bacteria. Significantly more effective than mechanical cleansing alone.
  • No resistance formation. Whitening effect instead of staining.
  • For continuous use with sustaining efficacy.

Enhance good dental hygiene using powerful KOITE® method

KOITE ® uses a Photodynamic Therapy based method where specific wavelengths of light activate a photosensitizer. In the presence of oxygen, this creates a reaction that kills harmful bacteria. Our photosensitizer adheres to dental plaque and the method is extremely effective against the most harmful Streptococcus species on the surface of teeth. It also reduces colonies of bacterial species known to cause periodontitis (gum disease), the most common cause of tooth loss among adults. Because the action is localized to teeth only, normal flora is preserved in other parts of the mouth.

1.
Untreated bacteria biofilm
2.
Chlorhexidine treated bacteria biofilm
3.
Chlorhexidine and Dual-Light PDT treated biofilm

Operational excellence

2M€

Funding acquired

+50 000

Antibacterial treatments sold

6

patent families established

Tommi Pätilä
M.D., Ph.D., Associate Professor in Pediatric Heart Surgery and Organ Transplantation

The compartmentalization involved in viewing the mouth separately from the rest of the body must cease. There is strong evidence proving that oral health affects general health."

Junnu Leikola
M.D., Ph.D., Oral and maxillofacial surgeon, Head of The Cleft Palate and Craniofacial Centre at the University of Helsinki, Finland

Koite Health is a promising new advancement in dental home care."

Jukka Meurman
M.D., PHD, DR. ODONT, DR. HC. (MULTI), FDSRCS.ED, Professor, Department of Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital

I greatly believe in the potential of the new prophylactic device to combat against oral infections. Even greater potential of the device is in the prevention of the secondary diseases arising from the compromised oral health"

Heikki Alapulli
M.D.

Koite Health provides a great opening to support pediatric dental hygiene. Sustaining oral bacterial diversity while reducing plaque bacteria is very appealing"

Regulatory

Koite Health is granted an ISO 13485 certification to design, develop and manufacture its antibacterial medical devices. Their intended use is the prevention and treatment of oral diseases and bacterial infections. ISO 13485 is the international quality management system standard for the design and production of medical devices. Koite Health is also ISO 9001 certified. Lumoral a class I medical device for prevention of oral diseases and is granted a CE marking. The product meets all relevant European Medical Device Directives and is also registered at Australian TGA.

 

 

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