Koite Health researchers have studied the efficacy and sustainability of the antibacterial effect of daily administered dual light on Streptococcus mutans biofilm. This was compared to single-wavelength antibacterial photodynamic therapy (aPDT) and antibacterial Blue light (aBL) treatments respectively.
The results indicate that when administered repeatedly to S. mutans biofilm, a single wavelength-based aBL or aPDT lead to a significant biofilm adaptation and increased S. mutans viability. The dual light, i. e. combined use of aBL light in synchrony with aPDT, arrests the adaptation and provides significantly improved and sustained antibacterial efficacy.
The results in the submitted article can be found here, in a pre-print medium for biologists, bioRxiv (“bio-archive”).